India’s First Gene-Edited Sheep

Current Context: Researchers from Sher-e-Kashmir University of Agricultural Sciences and Technology, in collaboration with the Indian Council of Agricultural Research, have developed India’s first gene-edited sheep using CRISPR-Cas9 technology.

About the Research:

• Technology Used: CRISPR-Cas9, a gene-editing tool that allows for precise modifications to DNA.
• Target Gene: Myostatin, a gene that regulates muscle growth. Editing this gene resulted in a 30% increase in muscle mass, a trait found in some European breeds but absent in Indian breeds.
• Significance: No foreign DNA was introduced, distinguishing it from transgenic organisms and potentially easing regulatory approvals.