October 25, 2025

ZyVac TCV

Current Context : Recently, ZyVac TCV, a typhoid vaccine developed by Zydus Lifesciences Ltd., has received prequalification from the World Health Organization (WHO), making it eligible for United Nations procurement programs.

About ZyVac TCV

  • Purpose: ZyVac TCV is a Typhoid Vi conjugate vaccine designed to provide immunity against Salmonella typhi, the bacterium responsible for typhoid fever.
  • How It Works: As a conjugate vaccine, it links bacterial antigens to polysaccharides (from the bacterial coat) to effectively trigger the body’s immune response.
  • Type: ZyVac TCV is a subunit vaccine, meaning it contains only specific bacterial components to stimulate immunity, minimizing side effects compared to whole-cell vaccines.
  • Made in India: The vaccine is fully developed and manufactured in India by Zydus Lifesciences Ltd., showcasing indigenous pharmaceutical capabilities.
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