BPaL regimen trial for TB

August 1, 2023

Over 85% cure rate has been seen in modified BPaL regimen trial for Tuberculosis.
The BPaL regimen is an all oral, short treatment course which uses only three drugs — bedaquiline, pretomanid and linezolid — and the treatment lasts only for 26 weeks.
- In contrast, conventional treatment for (Drug resistant)DR-TB, requires 8-9 tablets to be taken each day for 18 months
The shorter duration of the BPaL regimen also means that people undergoing the treatment cannot miss even one dose. In short, treatment adherence should be very good.
India is targeting to reduce TB incidence by 80% and TB deaths by 90% by 2025.